Type VI collagen and glycoprotein MFPI are distinct components of the extracellular matrix.

Type VI collagen and glycoprotein MFPI are distinct components of the extracellular matrix.
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VI 型胶原蛋白和糖蛋白 MFPI 是细胞外基质的不同成分。

DOI:
10.1042/bj2360299
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发表时间:
1986
期刊:
The Biochemical journal
影响因子:
--
通讯作者:
M. Grant
M. Grant
中科院分区:
--
文献类型:
--
作者:
S. Ayad;C. Chambers;L. Berry;C. Shuttleworth;M. Grant

文献摘要

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合成了两种胶原糖蛋白,MR 140,000和MR 150,000,并分泌到培养的成纤维细胞的培养液中。根据免疫学和物理化学标准,MR 140,000的糖蛋白与VI型胶原的140K(VI)组分相同。MR 150,000的糖蛋白在免疫学上是不同的,并表现出假定的弹性微纤维糖蛋白MFPI的物理化学特征。
Two collagenous glycoproteins, Mr 140,000 and Mr 150,000, are synthesized and secreted into the medium of cultured fibroblasts. The glycoprotein of Mr 140,000 is identical with the 140K(VI) component of type VI collagen by both immunological and physicochemical criteria. The glycoprotein of Mr 150,000 is immunologically distinct and exhibits the physicochemical characteristics of the putative elastic microfibrillar glycoprotein MFPI.