Brugada syndrome: 1992-2002 - A historical perspective
Brugada syndrome: 1992-2002 - A historical perspective
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DOI：
10.1016/s0735-1097(03)00310-3
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发表时间：
2003-05-21
影响因子：
24
通讯作者：
Nademanee, K
中科院分区：
文献类型：
--
作者：
Antzelevitch, C;Brugada, P;Nademanee, K
1992年，Pedro和Josep Brugada描述了一种有趣的新的临床实体，其特征是右胸导联ST段抬高，心脏结构正常的个体猝死的发生率很高。在过去的十年里，报告的病例数量呈指数级增长，用于定义这种疾病的临床、遗传、细胞、离子和分子方面的论文急剧增加。这篇简短回顾的目的是记录我们对Brugada综合征的历史亮点，这些历史亮点使我们对Brugada综合征有了现在的了解。(C)2003年，由美国心脏病学会基金会提供。
An intriguing new clinical entity characterized by ST-segment elevation in the right precordial electrocardiographic leads and a high incidence of sudden death in individuals with structurally normal hearts was described by Pedro and Josep Brugada in 1992. The past decade has witnessed an exponential rise in the number of reported cases and a dramatic proliferation of papers serving to define the clinical, genetic, cellular, ionic, and molecular aspects of this disease. The purpose of this brief review is to chronicle the historical highlights that have brought us to our present understanding of Brugada syndrome. (C) 2003 by the American College of Cardiology Foundation.