Using SomaticSniper to Detect Somatic Single Nucleotide Variants.
Using SomaticSniper to Detect Somatic Single Nucleotide Variants.
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DOI：
10.1002/0471250953.bi1505s45
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发表时间：
2014
影响因子：
--
通讯作者：
Wilson, Richard K
中科院分区：
文献类型：
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作者：
Larson, David E;Abbott, Travis E;Wilson, Richard K
利用下一代测序数据检测体细胞单核苷酸变异（SNV）是癌症研究的一个重要组成部分。本实验方案描述了如何运行SomaticSniper体细胞SNV检测工具，然后对输出结果进行筛选以去除大多数假阳性。它还包括详细介绍软件编译的支持性实验方案。
Detecting somatic single nucleotide variants (SNVs) is an essential component of cancer research with next generation sequencing data. This protocol describes how to run the SomaticSniper somatic SNV detector and then filter the output to eliminate most false positives. It also includes support protocols detailing the compilation of the software.