Frequency-dependent transversal flow control in centrifugal microfluidics
Frequency-dependent transversal flow control in centrifugal microfluidics
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DOI：
10.1039/b406699e
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发表时间：
2005-01-01
期刊：
影响因子：
6.1
通讯作者：
Ducrée, J
中科院分区：
文献类型：
--
作者：
Brenner, T;Glatzel, T;Ducrée, J
本文提出了一种新型的离心式微流控平台流量开关，该流量开关仅由科里奥利伪力控制。该科氏开关由一个反向Y型结构组成，该结构具有一个公共上游通道和旋转盘上的两个对称出口。在某一阈值频率以上，科里奥利力变得占主导地位，使得整个流转向到由旋转方向选择的出口之一中。对于360 mm的沟道宽度和125 μ m的深度，阈值频率已被测量为350 rad s（-1）（类似于55.7 Hz）。结果得到了广泛的CFD模拟的支持。
This work presents a novel flow switch for centrifugal microfluidic platforms which is solely controlled by the Coriolis pseudo force. This Coriolis switch consists of an inverse Y-structure with one common upstream channel and two symmetric outlets on a rotating disk. Above a certain threshold frequency, the Coriolis force becomes dominant that the entire flow is diverted into one of the outlets which is selected by the direction of rotation. The threshold frequency has been measured to be 350 rad s(-1) (similar to55.7 Hz) for a channel width of 360 mm and a depth of 125 mum. The results are supported by extensive CFD simulations.