Hydroxychloroquine-associated, photo-induced toxic epidermal necrolysis

Hydroxychloroquine-associated, photo-induced toxic epidermal necrolysis
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DOI:
10.1111/j.1365-2230.2008.02704.x
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发表时间:
2008-09-01
影响因子:
4.1
通讯作者:
Rogers, S.
Rogers, S.
中科院分区:
医学4区
文献类型:
--
作者:
Callaly, E. L.;FitzGerald, O.;Rogers, S.

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一名患者出现了中毒性表皮坏死松解症(TEN),这是由于患者长期服用羟基氯喹时暴露在阳光下而引发的。已知羟基氯喹会发生光毒性和光过敏反应,但据我们所知,这是第一例与该药物相关的光致过敏反应。
A patient developed toxic epidermal necrolysis (TEN), which was triggered by sun exposure while the patient was on long-term hydroxychloroquine. Phototoxic and photoallergic reactions are known to occur with hydroxychloroquine, but, to our knowledge, this is the first reported case of photo-induced TEN associated with the drug.