Morphometric measurements of the cranium in patients with Chiari type I malformation and comparison with the normal population
Morphometric measurements of the cranium in patients with Chiari type I malformation and comparison with the normal population
复制标题
DOI：
10.1007/s007010200020
复制
发表时间：
2002-01-01
影响因子：
2.4
通讯作者：
Sencer, SK
中科院分区：
文献类型：
--
作者：
Karagöz, F;Izgi, N;Sencer, SK
背景通过形态测量确定基亚里I型畸形患者后颅窝的发育程度和枕叶发育不良的体征。对22例基亚里Ⅰ型畸形患者的颅后窝进行了测量，并与21例正常人的颅后窝进行了比较。基亚里I型畸形患者的后颅窝深度、反映枕底发育的斜坡长度和Klaus指数均明显短于正常人（分别为p <0.001、p = 0.007和p < 0.001）。基亚里组的后颅窝深度与幕上区高度的比值以及反映后颅窝前后距离的Twining线也明显较小（两者均为p < 0.001）。在矢状面上，后颅窝骨性部分的表面积和该面积与幕上区域面积的比率显著小于正常受试者（分别为p = 0.038和p = 0.002）。颅底的角度测量（基底角、Boogard角和鼻根-基底-后凸角）显示，基亚里组中存在明显的基础平坦趋势（p = 0.04 p = 0.004）。p < 0.001）。此外，通过测量小脑幕缠绕线角，显示基亚里组的小脑幕比正常人更陡峭。这些结果支持了基亚里I型畸形患者存在枕骨和后颅窝发育不全的观点。
Background To determine the degree of development of the posterior fossa and signs of occipital dysplasia in patients with Chiari type I malformation by morphometric measurements.Methods. In 22 patients with Chiari type I malformation, distance, surface area and angle values reflecting the degree of development of the posterior fossa were measured and compared with the measurements of 21 normal subjects.Findings. In patients with Chiari type I malformation, the depth of the posterior fossa, the length of the clivus reflecting development of the basi-occiput and Klaus' index were significantly shorter than in normal subjects (p < 0.00 1, p = 0.007, and p < 0.001, respectively). The ratios of the depth of the posterior fossa to the height of the supratentorial region and Twining's line reflecting anteroposterior distance of the posterior fossa were also significantly smaller in the Chiari group (p < 0.001 for both). In sagittal section, the surface area of the bony part of the posterior fossa and the ratio of this area to the area of the supratentorial region were significantly smaller than in normal subjects (p = 0.038 and p = 0.002, respectively). The angle measurements of the cranial base (basal angle, Boogard's angle and nasion-basion-opisthion angle) showed that there was an evident tendency for platibasia in the Chiari group (p = 0.04 p = 0.004. p < 0.001, respectively). In addition, it was shown by measuring tentorium-twining's line angle that the tentorium was steeper in the Chiari group than normal subjects.Interpretation. These results support the opinion, which claims the existence of underdevelopment of the occipital bone and posterior fossa in patients with Chiari type I malformation.