P34HB electrospun fibres promote bone regeneration in vivo
P34HB electrospun fibres promote bone regeneration in vivo
复制标题
P34HB 电纺纤维促进体内骨再生。
DOI：
10.1111/cpr.12601
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发表时间：
2019-05-01
影响因子：
8.5
通讯作者：
Cai, Xiaoxiao
中科院分区：
文献类型：
--
作者：
Fu, Na;Meng, Zhaosong;Cai, Xiaoxiao
骨组织工程于1995年问世，为骨重建和骨缺损的修复提供了新的途径。然而，合适的仿生骨支架的设计和制造仍然具有挑战性，理想的骨组织工程支架应该具有三维多孔网络、良好的生物相容性和良好的生物降解性等。本研究的目的是探讨bioplasticpoly3‐hydroxybutyrate4‐hydroxybutyrate(P34HB)电纺纤维支架是否有利于骨缺损的修复，以及它是否有可能成为骨组织工程的支架。
Bone tissue engineering was introduced in 1995 and provides a new way to reconstruct bone and repair bone defects. However, the design and fabrication of suitable bionic bone scaffolds are still challenging, and the ideal scaffolds in bone tissue engineering should have a three‐dimensional porous network, good biocompatibility, excellent biodegradability and so on. The purpose of our research was to investigate whether a bioplasticpoly3‐hydroxybutyrate4‐hydroxybutyrate (P34HB) electrospun fibre scaffold is conducive to the repair of bone defects, and whether it is a potential scaffold for bone tissue engineering.