Novel PSMA-Coated On-Off-On Fluorescent Chemosensor Based on Organic Dots with AIEgens for Detection of Copper (II), Iron (III) and Cysteine
Novel PSMA-Coated On-Off-On Fluorescent Chemosensor Based on Organic Dots with AIEgens for Detection of Copper (II), Iron (III) and Cysteine
复制标题
基于有机点和 AIEgens 的新型 PSMA 涂层 On-Off-On 荧光化学传感器，用于检测铜 (II)、铁 (III) 和半胱氨酸
DOI：
10.3390/polym10070786
复制
发表时间：
2018-07-01
期刊：
影响因子：
5
通讯作者：
Zhang, Yan
中科院分区：
文献类型：
--
作者：
Jiang, Rui;Liu, Na;Zhang, Yan
为此，利用纳米沉淀法研制了一种新型的铜(II)离子(Cu2+)、铁(III)离子(Fe3+)和半胱氨酸的开关开关荧光化学传感器。与其他金属离子相比，所制备的含AIEgen的有机点(AIE点)在检测Cu2+、Fe3+时具有较高的选择性和灵敏度，可形成团聚(开-关)。在半胱氨酸存在下，AIE斑点与Cu2+形成的团聚重新分布，荧光明显恢复(OFF-ON)。该传感器对Cu2+、Fe3+和半胱氨酸有较宽的线性范围。对Cu2+、Fe3+和半胱氨酸的荧光检测限分别为107 nM、120 nM和78 nM。这些结果表明，AIE斑点可以作为检测Cu2+、Fe3+和半胱氨酸的潜在探针。
Herein, a novel on-off-on fluorescent chemosensor for copper (II) ion (Cu2+), iron (III) ion (Fe3+) and cysteine is developed simply by the nano-precipitation method. The prepared organic dots with AIEgens (AIE dots) are advantageous over other metal ions in detecting Cu2+, Fe3+ with high selectivity and sensitivity by forming agglomerations (on-off). The agglomerations formed by AIE dots and Cu2+ redistributed and the fluorescence was obviously recovered in the presence of cysteine (off-on). This sensor has a wide linear range for Cu2+, Fe3+ and cysteine. The fluorescent detection limits of AIE dots are calculated to be 107 nM for Cu2+, 120 nM for Fe3+ and 78 nM for cysteine, respectively. These results indicate that the AIE dots can be used as a potential probe for Cu2+, Fe3+ and cysteine detection.