Somatotopy of the lateral line projection in larval zebrafish
Somatotopy of the lateral line projection in larval zebrafish
复制标题
DOI：
10.1073/pnas.96.13.7558
复制
发表时间：
1999-06-22
影响因子：
11.1
通讯作者：
Ghysen, A
中科院分区：
文献类型：
--
作者：
Alexandre, D;Ghysen, A
我们用双标记法研究了斑马鱼仔鱼侧线初级投射的地形。后侧线的两个确定的神经肥大的预测被看作是两个独立的组的纤维，显示可再现的空间关系：前神经肥大的投影总是腹外侧的一个更后定位的神经肥大。同样的规则也适用于前侧线神经瘤的投射。因此，感觉神经元的中央投射代表了神经乳突沿着鱼的前后轴的位置。这somatotopy是类似的，并可能是在起源，在哺乳动物耳蜗毛细胞的tonotopic投影。
We examined the topography of the lateral line primary projection in zebrafish larvae by double labeling. The projections of two identified neuromasts of the posterior lateral line are seen as two separate sets of fibers that show reproducible spatial relationships: the projection of the anterior neuromast is always ventrolateral to that of a more posteriorly located neuromast. The same rule applies to the projection of anterior lateral line neuromasts. The position of the neuromasts along the antero posterior axis of the fish therefore is represented in the central projection of the sensory neurons. This somatotopy is similar to, and may be at the origin of, the tonotopic projection of the cochlear hair cells in mammals.