Spindly attachments
Spindly attachments
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DOI：
10.1101/gad.1719208
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发表时间：
2008-09-01
影响因子：
10.5
通讯作者：
Musacchio, Andrea
中科院分区：
文献类型：
--
作者：
Civril, Filiz;Musacchio, Andrea
在有丝分裂过程中，染色体与纺锤体微管的连接是一个微妙而复杂的过程，真核细胞非常依赖于此来维持其倍性。在这一期的《基因与发育》杂志上，Gassmann和他的同事们（pp. 2385-2399）提出了对最近发现的Spindly/SPDL-1蛋白的分析，该蛋白对附着过程及其与细胞周期进程控制相关的方式有了新的认识。
The attachment of chromosomes to spindle microtubules during mitosis is a delicate and intricate process on which eukaryotic cells critically depend to maintain their ploidy. In this issue of Genes & Development, Gassmann and colleagues ( pp. 2385-2399) present an analysis of the recently discovered Spindly/SPDL-1 protein that casts new lights onto the attachment process and the way it relates to the control of cell cycle progression.