Differentiating 131I Radiation Sialadenitis From Autoimmune (Sjogren Syndrome) Sialadenitis: Case Report
Differentiating 131I Radiation Sialadenitis From Autoimmune (Sjogren Syndrome) Sialadenitis: Case Report
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DOI：
10.1016/j.joms.2017.04.008
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发表时间：
2017-11-01
影响因子：
1.9
通讯作者：
Greene, Loren Wissner
中科院分区：
文献类型：
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作者：
Mandel, Louis;Greene, Loren Wissner
放射性碘（I-131）可有效用于治疗分化型甲状腺癌。因为它是由唾液腺主动分泌的，所以可能会对这些腺体造成辐射损伤。餐时唾液刺激后阻塞性唾液腺炎是常见的情况。如果使用低剂量的I-131，通常不会出现口干。经证明，接受I-131 75.8 mCi治疗的患者的口干症的主观主诉与同时存在的干燥综合征（SS）有关。血清学、组织学、唾液腺造影和唾液量结果以及患者的主观主诉有助于确定先前存在SS。(C)2017年美国口腔颌面外科医师协会
Radioactive iodine (I-131) is used effectively for the treatment of differentiated thyroid cancers. Because it is actively secreted by the salivary glands, radiation damage to these glands can occur. Obstructive swellings after mealtime salivary stimulation are common occurrences. Dry mouth is not usually seen if low doses of I-131 are used. A subjective complaint of xerostomia in a patient treated with I-131 75.8 mCi proved to be related to the simultaneous presence of Sjogren syndrome (SS). Serologic, histologic, scintigraphic, and salivary volume findings and the patient's subjective complaints served to establish the pre-existence of SS. (C) 2017 American Association of Oral and Maxillofacial Surgeons