THE IMPACT OF BLUETONGUE VIRUS ON REPRODUCTION
THE IMPACT OF BLUETONGUE VIRUS ON REPRODUCTION
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DOI：
10.1016/0147-9571(94)90042-6
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发表时间：
1994-08-01
影响因子：
2
通讯作者：
OSBURN, BI
中科院分区：
文献类型：
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作者：
OSBURN, BI
蓝舌病病毒是反刍动物的一种重要的非接触性、节肢动物传染性病毒病。 全世界已经确认了24种不同的病毒血清型。 最严重的临床疾病与绵羊和一些自由放养的野生反刍动物的严重临床疾病有关。 一些报告暗示这些病毒会引起男性和女性的生殖障碍。 与蓝舌病有关的生殖障碍包括早期胚胎死亡、流产、畸形的胎牛或胎羊、公牛和公羊的暂时性不育以及精液中的病毒脱落。 最近，蓝舌病病毒污染的改良活犬疫苗与流产和急性死亡的怀孕母犬。 本文讨论了生殖失败的这些不同方面的发病机制。
Bluetongue virus has been recognized as an important noncontagious, arthropodborne infectious viral disease of ruminants. 24 different serotypes of virus have been recognized worldwide. The most severe clinical disease has been associated with severe clinical disease in sheep and some free ranging wild ruminants. A number of reports have implicated the viruses as causing reproductive disorders in both males and females. The bluetongue related reproductive disorders include early embryonic deaths, abortions, malformed fetal calves or lambs, transient infertility in bulls and rams, and shedding of virus in semen. Recently, bluetongue virus contamination of modified live commercial canine vaccine was associated with abortion and acute death of pregnant bitches. The pathogenesis of these various aspects of reproductive failure are discussed herein.