Insect Neuropeptides of the Pyrokinin/PBAN Family Accelerate Pupariation in the Fleshfly (Sarcophaga bullata) Larvae a
Insect Neuropeptides of the Pyrokinin/PBAN Family Accelerate Pupariation in the Fleshfly (Sarcophaga bullata) Larvae a
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DOI：
10.1111/j.1749-6632.1997.tb46145.x
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发表时间：
1997-04
影响因子：
5.2
通讯作者：
Jan Žďárek;R. Nachman;T. K. Hayes
中科院分区：
文献类型：
--
作者：
Jan Žďárek;R. Nachman;T. K. Hayes
Neuropeptides that regulate various aspects of insect homeostasis have been isolated from several orders of insects.' Comparison of the chemical sequences revealed some common features among many of these peptides. Therefore it is not surprising that the same class of neuropeptides may serve different physiological and behavioral functions. For example, the pyrokinin/PBAN family of neuropeptides, originally identified as myotropins from orthopteroid insect^,^,^ appears to be widespread in several insect orders. Its members were found to serve such diverse functions as the induction of sex pheromone production in various female moths,4 contraction of the locust o ~ i d u c t , ~ melanization and reddish coloration in caterpillar^,^ and egg diapause in the silkworm.6 Although these pyrokinin peptides have different numbers of amino acids,7 they share the common C-terminal sequence FXPRLamide (X = G, S, T or V). The pentapeptide fragment proved to be the active core required not only for myotropic activity in the cockroach hindgut assay,8 but also for phe romono t r~p ic~~ '~ and melanotropic a ~ t i v i t y , ~ and egg diapause inducing activity in the silkworm.6~11 The existence of cross activity of pyrokinin neuropeptides prompted us to screen various synthetic arthropod neuropeptides, including those of the pyrokinin/PBAN family, for the ability to accelerate formation of the pupanum (pupariation) in larvae of the fleshfly, Sarcophaga bullata, a developmental process known to be under neuroendocrine control.'2
