HSP70 heat shock proteins and environmental stress in Antarctic marine organisms: A mini-review
HSP70 heat shock proteins and environmental stress in Antarctic marine organisms: A mini-review
复制标题
DOI：
10.1016/j.margen.2009.03.003
复制
发表时间：
2009-03-01
期刊：
影响因子：
1.9
通讯作者：
Peck, Lloyd S.
中科院分区：
文献类型：
--
作者：
Clark, Melody S.;Peck, Lloyd S.
在我们不断变化的环境中，理解和预测环境压力对生物多样性的影响的能力变得越来越重要。南极海洋物种是地球上温度最低的物种之一，许多栖息在南极半岛附近的沃茨，这是区域气候变化迅速的地区之一。因此，这些动物非常容易受到环境温度变化的影响，显然我们需要了解它们反应的复杂性，不仅是在单个物种的水平上，而且对整个生态系统的影响。热休克蛋白在生物应激反应的研究中有着悠久的历史，并且经常被提议作为潜在的通用分子生物标志物，特别是对于非模式物种。在这篇小型综述中，热休克反应和热休克蛋白（特别是HSP70家族）在南极海洋物种中进行了研究，同时研究了它们的生理能力和限制，以回答一系列问题：这些动物是否具有包括HSP70基因表达的热休克反应？它们的热休克反应和生理能力之间有什么关系？HSP70基因能否作为这些物种的分子生物标志物？皇冠版权所有（C）2009由Elsevier B.V.出版。保留所有权利
The ability to understand and predict the effects of environmental stress on biodiversity is becoming increasingly important in our changing environment. Antarctic marine species are some of the most stenothermal on the planet and many inhabit the waters off the Antarctic Peninsula which is one of the areas where there is rapid regional climate change. Therefore these animals are highly vulnerable to changing environmental temperatures and clearly we need to understand the complexities of their response, not just at the individual species level, but also the implications for the ecosystem as a whole. Heat shock proteins have a long history of use in studies of organism stress responses and have frequently been proposed as potential universal molecular biomarkers, especially for non-model species. In this mini-review, the heat shock response and heat shock proteins (specifically the HSP70 family) are examined in Antarctic marine species alongside their physiological capabilities and limits to answer a series of questions: do these animals have a heat shock response which includes the expression of HSP70 genes? What is the relationship between their heat shock response and physiological capabilities? Can HSP70 genes be used as molecular biomarkers for these species? Crown Copyright (C) 2009 Published by Elsevier B.V. All rights reserved