Hematological complications and quality of life in hospitalized AIDS patients
Hematological complications and quality of life in hospitalized AIDS patients
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DOI：
10.1089/108729100317731
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发表时间：
2000-05-01
影响因子：
4.9
通讯作者：
Portillo, CJ
中科院分区：
文献类型：
--
作者：
Cosby, C;Holzemer, WL;Portillo, CJ
艾滋病血细胞减少的生物学和生理学指标与生活质量指标之间的关系尚未得到很好的表征。二次分析的目的是确定贫血、中性粒细胞减少症和血小板减少症与艾滋病患者的个体特征、生理标志物、症状、功能状态、一般健康感知和幸福感之间的关系。Wilson和Cleary健康相关生活质量模型的五个维度为本研究提供了概念模型。除描述性统计外，还使用逻辑回归分析变量群。样本的146例住院艾滋病患者有85%的患病率贫血，53%的患病率中性粒细胞减少和33%的患病率血小板减少。平均年龄为38岁，19%为女性，35%为白色，27%有注射吸毒史，平均辅助性T细胞计数为74 mm（3）。Wilson和Cleary模型的五个维度仅为贫血提供了显著的预测性。症状评分较高的患者更有可能患有可治疗的贫血，定义为红细胞压积为
The relationships among the biological and physiological indicators of cytopenias in AIDS and measures of quality of life are not well characterized. The purpose of this secondary analysis was to determine the relationships among anemia, neutropenia and thrombocytopenia and characteristics of the individual, physiological markers, symptoms, functional status, general health perceptions, and well-being in people with AIDS. The five dimensions of the Wilson and Cleary model of health-related quality of life provided the conceptual model for this study. In addition to descriptive statistics, logistic regression was used to analyze clusters of variables. The sample of 146 hospitalized patients with AIDS had an 85% prevalence of anemia, a 53% prevalence neutropenia and a 33% prevalence of thrombocytopenia. The mean age was 38 years old, 19% were female, 35% were white, 27% had a history of injection drug use and the mean T-helper cell count was 74 mm(3). The five dimensions of the Wilson and Cleary model offered significant predictability for anemia only. Patients with higher symptom scores were more likely to have treatable anemia, defined as a hematocrit of