REGULATION OF ENERGY BALANCE

REGULATION OF ENERGY BALANCE
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DOI:
10.1038/222629a0
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发表时间:
1969-01-01
期刊:
影响因子:
64.8
通讯作者:
HERVEY, GR
HERVEY, GR
中科院分区:
综合性期刊1区
文献类型:
--
作者:
HERVEY, GR

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在成年人中,维持几乎恒定的正常体脂肪量,从而维持几乎恒定的体重,需要一定精确的生理调节。审查了这种控制的机制。通过共生大鼠获得了一些证据,表明能量平衡的调节涉及体内长期持续存在的激素反馈信号。有人建议,一种合适的激素可以为身体提供一种通过稀释来测量储存脂肪量的方法;这种示踪剂可能是类固醇。已知几种类固醇激素的产生是由反馈机制控制的。-D. L.D.
In adults the maintenance of a nearly constant normal amount of body fat, and therefore a nearly constant bodyweight, requires physiological regulation of some precision. The mechanisms of such control are reviewed. Some evidence that regulation of energy balance involves a hormonal feedback signal with a long persistence in the body has been obtained with parabiotic rats. It is suggested that a suitable hormone might provide the body with a means of measuring the amount of fat in store by its dilution; such a tracer might be a steroid. Production of several steroid hormones is known to be controlled by feedback mechanisms.-D. L. D.