Experimental antimicrobial orthodontic adhesives using nanofillers and silver nanoparticles
Experimental antimicrobial orthodontic adhesives using nanofillers and silver nanoparticles
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DOI：
10.1016/j.dental.2008.06.002
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发表时间：
2009-02-01
期刊：
影响因子：
5
通讯作者：
Lim, Bum-Soon
中科院分区：
文献类型：
--
作者：
Ahn, Sug-Joon;Lee, Shin-Jae;Lim, Bum-Soon
目的：比较含纳米二氧化硅和银纳米粒子的实验性复合粘接剂（ECAs）与两种传统粘接剂（复合粘接剂和树脂改性玻璃离子[RMGI]）的表面特征、物理性能和对致龋链球菌的抗菌活性。表面粗糙度和表面自由能（SFE）的特性，采用共聚焦激光扫描显微镜和座滴法测量。通过剪切粘结强度和粘结破坏界面的分析比较两种材料的物理性能。通过细菌粘附试验、纸片扩散试验和含有每种粘合剂的细菌悬液的光密度测量来分析抗菌活性。由于添加了银纳米颗粒，ECA具有比常规粘合剂更粗糙的表面。ECAs与复合材料的SFE特征比RMGI更相似。ECAs的细菌粘附性低于传统的粘合剂，这是不受唾液涂层。含有ECA的细菌悬浮液比含有常规粘合剂的细菌生长慢。ECAs与传统粘接剂的剪切粘接强度和粘接失效界面无显著性差异。这项研究表明，ECA可以帮助防止釉质脱矿周围的表面，而不损害物理性能。(c)2008年，牙科材料学院。由爱思唯尔有限公司出版。保留所有权利。
Objectives, Experimental composite adhesives (ECAs) containing silica nanofillers and silver nanoparticles were compared with two conventional adhesives (composite and resin-modified glass ionomer [RMGI]) to analyze surface characteristics, physical properties and antibacterial activities against cariogenic streptococci.Methods. Surface roughness and surface free energy (SFE) characteristics were measured using confocal laser scanning microscopy and the sessile drop method. Shearbond strength and bond failure interface were analyzed to compare the physical properties. Antimicrobial activities were analyzed by a bacterial adhesion assay, a disk diffusion test, and an optical density measurement of bacterial suspension containing each adhesive.Results. ECAs had rougher surfaces than conventional adhesives due to the addition of silver nanoparticles. ECAs had more similar SFE characteristics to composite than to RMGI. Bacterial adhesion to ECAs was less than to conventional adhesives, which was not influenced by saliva coating. Bacterial suspension containing ECAs showed slower bacterial growth than those containing conventional adhesives. There was no significant difference in shear bond strength and bond failure interface between ECAs and conventional adhesives.Significance. This study suggests that ECAs can help prevent enamel demineralization around their surfaces without compromising physical proper-ties. (c) 2008 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.