Visual Input into the Drosophila melanogaster Mushroom Body.

Visual Input into the Drosophila melanogaster Mushroom Body.
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DOI:
10.1016/j.celrep.2020.108138
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发表时间:
2020-09-15
期刊:
影响因子:
8.8
通讯作者:
Caron SJC
Caron SJC
中科院分区:
生物学1区
文献类型:
--
作者:
Li J;Mahoney BD;Jacob MS;Caron SJC

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多感觉整合是许多大脑的基本特性,其背后的神经元连接模式仍然缺乏特征。果蝇蘑菇体是研究不同感觉通道如何在高级脑中心会聚的理想系统。连接蘑菇体和嗅觉系统的神经元已经被详细描述,但是来自其他感觉系统的输入仍然不清楚。在这里,我们使用一系列的解剖和遗传技术,以确定两种类型的输入神经元连接视觉处理中心的小叶和后外侧前脑的蘑菇体的背侧副萼。与以前的工作,描述了一个途径,从延髓到腹侧副萼的蘑菇体的视觉信息传递,我们的研究定义了第二个,平行的途径,是解剖学上准备传递信息从视觉系统到背侧副萼。Li等人发现果蝇蘑菇体的背侧副萼整合了来自小叶和后外侧前脑的视觉输入。
The patterns of neuronal connectivity underlying multisensory integration, a fundamental property of many brains, remain poorly characterized. The Drosophila melanogaster mushroom body—an associative center—is an ideal system to investigate how different sensory channels converge in higher order brain centers. The neurons connecting the mushroom body to the olfactory system have been described in great detail, but input from other sensory systems remains poorly defined. Here, we use a range of anatomical and genetic techniques to identify two types of input neuron that connect visual processing centers—the lobula and the posterior lateral protocerebrum—to the dorsal accessory calyx of the mushroom body. Together with previous work that described a pathway conveying visual information from the medulla to the ventral accessory calyx of the mushroom body, our study defines a second, parallel pathway that is anatomically poised to convey information from the visual system to the dorsal accessory calyx. Li et al. find that the dorsal accessory calyx of the Drosophila melanogaster mushroom body integrates visual input from the lobula and the posterior lateral protocerebrum.
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