Effects of a malaria elimination program: a retrospective study of 623 cases from 2008 to 2013 in a Chinese county hospital near the China--Myanmar border.
Effects of a malaria elimination program: a retrospective study of 623 cases from 2008 to 2013 in a Chinese county hospital near the China--Myanmar border.
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DOI：
10.1038/emi.2016.6
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发表时间：
2016-01-20
影响因子：
13.2
通讯作者：
Zhang W
中科院分区：
文献类型：
--
作者：
Wang X;Yang L;Jiang T;Zhang B;Wang S;Wu X;Wang T;Li Y;Liu M;Peng Q;Zhang W
自2010年中国从疟疾控制项目转向消除疟疾战略以来，中国西南地区与缅甸接壤，是输入性疟疾病例最多的地区。我们进行了一项回顾性研究，分析了623份医学图表，以提供2008年至2013年在中国西南部腾冲县人民医院（PHTC）诊断和治疗的疟疾病例的流行病学特征。我们的目的是了解该地区疟疾的特点，该地区是一个有输入病例的高流行地区。患者以男性居多（91.7%），平均年龄32.4岁。86.4%的患者曾到过缅甸；分娩是63.9%患者旅行的目的。间日疟原虫和恶性疟原虫的感染率分别为53.8%和34.9%。住院人数从2008年到2010年逐渐上升，2010年达到高峰（191人）。2010年后，住院病例从2010年的191例迅速下降到2013年的45例，居住在森林中的患者比例和感染恶性疟原虫的人数也有所下降。综上所述，2010年中国实施消除疟疾战略后，中国西南地区腾冲县的住院患者数量有所下降。然而，从缅甸返回的移徙工人仍然是造成输入性疟疾病例的重要因素。输入性疟疾的管理应成为中国消除疟疾规划的目标。
The southwestern region of China, along the Myanmar border, has accounted for the highest number of cases of imported malaria since China shifted from a malaria control program to an elimination strategy in 2010. We conducted a retrospective study, in which 623 medical charts were analyzed to provide an epidemiological characterization of malaria cases that were diagnosed and treated at the People's Hospital of Tengchong County (PHTC), located in southwestern China, from 2008 to 2013. Our aim was to understand the characteristics of malaria in this region, which is a high-endemic region with imported cases. The majority of patients were male (91.7%), and the average age was 32.4 years. Most of the patients (86.4%) had visited Myanmar; labor was the purpose of travel for 63.9% of the patients. Plasmodium vivax and Plasmodium falciparum were responsible for 53.8% and 34.9% of the infections, respectively. The number of hospitalized patients rose gradually from 2008 to 2010 and reached its peak in 2010 (191). After 2010, the number of hospitalized cases fell rapidly from 191 (2010) to 45 (2013), and the proportion of patients who lived in the forest and the number infected with P. falciparum also fell. In conclusion, the number of hospitalized patients in the southwestern region of China, Tengchong county, decreased after China implemented a malaria elimination strategy in 2010. However, migrant workers returning from Myanmar remained important contributors to cases of imported malaria. The management of imported malaria should be targeted by the malaria elimination program in China.