Quantitative measurements of radioiodine retention in thyroid carcinoma.
Quantitative measurements of radioiodine retention in thyroid carcinoma.
复制标题
甲状腺癌中放射性碘保留的定量测量。
DOI：
10.1210/jcem-14-11-1300
复制
发表时间：
1954
影响因子：
5.8
通讯作者：
G. Hilton
中科院分区：
文献类型：
--
作者：
E. Pochin;R. M. Cunningham;G. Hilton
在放射性碘治疗过程中，我们一直有兴趣测量功能性甲状腺癌的放射性碘滞留量，主要有两个原因：1)找出滞留程度如何随剂量的变化，以及这一测量是否提供了治疗进展的标准；2)确定这些肿瘤中放射性碘周转的速度，因为这与每个剂量所发射的辐射量有关。为了这两个目的，需要一种快速和可靠的方法来在每次剂量后每天测量肿瘤或其转移的放射性碘含量，并在治疗期间每年在类似的条件下测量肿瘤的放射性碘含量。为了达到这一目的，我们用以下方法对一组功能性肿瘤患者进行了超过两年半的连续测量：方法患者躺在沙发上，柜台水平移动，在沿线的点上测定计数率。
DURING the course of radioiodine therapy, we have been interested in measuring the amount of radioiodine retention in functioning thyroid carcinomas for two main reasons: 1) to find how the degree of retention changes from dose to dose, and whether this measurement offers a criterion as to the progress of treatment, and 2) to determine the speed of radioiodine turnover in these tumors, since this is relevant to the amount of radiation delivered by each dose. For both of these purposes, a rapid and robust method is needed for measuring the radioiodine content of the tumor or of its metastases daily after each dose, and under comparable conditions from year to year during treatment. Several procedures might be used for this purpose, and we have obtained serial measurements extending over two and a half years in a group of patients with functioning tumors by the following method: METHODS The patient lies on a couch over which a counter is moved horizontally, the counting rate being determined at points along...