The effect of high evening blood pressure on obstructive sleep apnea-related morning blood pressure elevation: does sex modify this interaction effect?
The effect of high evening blood pressure on obstructive sleep apnea-related morning blood pressure elevation: does sex modify this interaction effect?
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DOI：
10.1007/s11325-019-01869-5
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发表时间：
2019-12-01
影响因子：
2.5
通讯作者：
Lee, Sang-Ahm
中科院分区：
文献类型：
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作者：
Han, Su-Hyun;Kim, Hyo Jae;Lee, Sang-Ahm
目的 阻塞性睡眠呼吸暂停 (OSA) 可导致早晨血压 (BP) 升高。我们假设夜间血压升高可能会加重 OSA 相关的早晨血压升高。此外，这种相互作用可能会因性别而改变。 方法 这项回顾性横断面研究纳入了新诊断的 OSA 患者，这些患者在整夜多导睡眠监测中呼吸暂停低通气指数 (AHI) ≥ 5/小时。使用协方差分析 (ANCOVA) 来确定重度 OSA (AHI >= 30) 是否与轻度至中度 OSA (5
Purpose Obstructive sleep apnea (OSA) can lead to increased morning blood pressure (BP). We hypothesized that high evening BP may aggravate OSA-related morning BP elevation. Additionally, this interactional effect may be modified by sex.Methods This retrospective, cross-sectional study included newly diagnosed OSA patients with an apnea-hypopnea index (AHI) >= 5 per hour on a full-night polysomnography. An analysis of covariance (ANCOVA) was used to determine whether severe OSA (AHI >= 30) was associated with higher morning BP than mild-to-moderate OSA (5