CELL SENSITIVITY TO GRAVITY
CELL SENSITIVITY TO GRAVITY
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DOI：
10.1126/science.6729481
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发表时间：
1984-01-01
期刊：
影响因子：
56.9
通讯作者：
FUCHSBISLIN, P
中科院分区：
文献类型：
--
作者：
COGOLI, A;TSCHOPP, A;FUCHSBISLIN, P
在微重力条件下暴露于有丝分裂原伴刀豆球蛋白A的人淋巴细胞培养物显示出低于地面对照的3%的活化。这一结果支持的假设，在低g和高g的实验，微重力抑制，而高重力增强细胞增殖率的模拟的基础上。重力的影响在正在分化的细胞中特别强烈。
Cultures of human lymphocytes exposed in microgravity to the mitogen concanavalin A showed < 3% of the activation of ground controls. This result supports the hypothesis, based on simulations at low g and experiments at high g, that microgravity depresses whereas high gravity enhances cell proliferation rates. The effects of gravity are particularly strong in cells undergoing differentiation.