Age-dependent changes in susceptibility of suckling mice to individual strains of Helicobacter pylori.
Age-dependent changes in susceptibility of suckling mice to individual strains of Helicobacter pylori.
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乳鼠对幽门螺杆菌个体菌株敏感性的年龄依赖性变化。
DOI：
10.1128/iai.73.2.1232-1234.2005
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发表时间：
2005
期刊：
影响因子：
--
通讯作者：
Berg,DouglasE
中科院分区：
文献类型：
--
作者：
Suto,Hiroyuki;Zhang,Maojun;Berg,DouglasE
为了建立婴儿幽门螺杆菌感染模型，将优先定植于不同胃区域并在体内共存的菌株混合物接种到乳鼠中。H. pylori恢复2周后的结果表明，某些品系的易感性比其他品系的易感性开始得更早，并且易感性的开始在小鼠品系之间存在差异。
To model establishment ofHelicobacter pyloriinfection in infants, suckling mice were inoculated with mixtures of strains that preferentially colonize different gastric regions and coexist in vivo. Characterization ofH. pylorirecovered 2 weeks later showed that susceptibility begins earlier for some strains than for others and that the onset of susceptibility varies among mouse lines.