Potential Pharmacological Resources: Natural Bioactive Compounds from Marine-Derived Fungi.
Potential Pharmacological Resources: Natural Bioactive Compounds from Marine-Derived Fungi.
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潜在的药理学资源：来自海洋真菌的天然生物活性化合物
DOI：
10.3390/md14040076
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发表时间：
2016-04-22
期刊：
影响因子：
5.4
通讯作者：
Fan S
中科院分区：
文献类型：
--
作者：
Jin L;Quan C;Hou X;Fan S
近年来，人们从海洋真菌中分离出了大量结构独特的具有生物学和药理学活性的代谢产物，如聚酮化合物、生物碱、多肽、内酯、萜类化合物和甾体等。这些化合物中的一些具有抗癌、抗细菌、抗真菌、抗病毒、抗炎、抗氧化、抗生素和细胞毒性特性。本文根据真菌的来源及其生物活性对海洋真菌中的新活性物质进行了分类。对2014年至今发现的真菌进行了讨论。
In recent years, a considerable number of structurally unique metabolites with biological and pharmacological activities have been isolated from the marine-derived fungi, such as polyketides, alkaloids, peptides, lactones, terpenoids and steroids. Some of these compounds have anticancer, antibacterial, antifungal, antiviral, anti-inflammatory, antioxidant, antibiotic and cytotoxic properties. This review partially summarizes the new bioactive compounds from marine-derived fungi with classification according to the sources of fungi and their biological activities. Those fungi found from 2014 to the present are discussed.