The vegetally localized mRNA fatvg is associated with the germ plasm in the early embryo and is later expressed in the fat body
The vegetally localized mRNA fatvg is associated with the germ plasm in the early embryo and is later expressed in the fat body
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DOI：
10.1016/s0925-4773(00)00517-7
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发表时间：
2001-01-01
影响因子：
2.6
通讯作者：
Etkin, LD
中科院分区：
文献类型：
--
作者：
Chan, AP;Kloc, M;Etkin, LD
爪蟾卵母细胞植物定位rna参与了原始生殖层的建立和原始生殖细胞的形成和发育。fatvg mRNA通过晚期通路定位到植物皮层。与Vg1 mRNA一样，fatvg分布于整个皮层；然而，与Vg1不同的是，有一小部分fatvg mRNA与线粒体云有关。在卵裂早期胚胎中，fatvg mRNA与位于胚胎植物卵裂球尖端的种质有关。虽然在胚胎的种质中发现了一些遵循信息传输组织者（METRO）途径的定位RNA，但fatvg是与种质相关的晚期途径RNA。在蝌蚪中，fatvg mRNA表现出一种不同于生殖细胞谱系的新表达模式，在两组细胞中沿中线的内胚层肿块的背前边缘被检测到。后来在发育中的脂肪体（青蛙的主要脂肪组织）中也检测到fatvg mRNA的表达。(C) 2001爱思唯尔科学爱尔兰有限公司版权所有。
Vegetally localized RNAs in Xenopus oocytes have been implicated in the establishment of the primary germ layers and the formation and development of the primordial germ cells. fatvg mRNA is localized through the late pathway to the vegetal cortex. Like Vg1 mRNA fatvg is distributed throughout the entire cortex; however, unlike Vg1 there is a small fraction of the fatvg mRNA that is associated with the mitochondrial cloud. In early cleavage stage embryos, fatvg mRNA is associated with the germ plasm located at the tips of the vegetal blastomeres of the embryo. While several localized RNAs that follow the Message Transport Organizer (METRO) pathway have been found in the germ plasm in embryos, fatvg is a late pathway RNA that is associated with the germ plasm. In tadpoles, fatvg mRNA shows a novel pattern of expression which is distinct from the germ cell lineage and is detected at the dorso-anterior margin of the endodermal mass along the midline in two clusters of cells. fatvg mRNA expression is also detected later in the developing fat bodies, the major adipose tissues of the frog. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.