Postnatal Maturation of Small Intestinal Motility in Preterm and Term Infants

Postnatal Maturation of Small Intestinal Motility in Preterm and Term Infants
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早产儿和足月儿小肠蠕动的出生后成熟

DOI:
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发表时间:
1989
期刊:
影响因子:
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通讯作者:
A. D. Hoffman
A. D. Hoffman
中科院分区:
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文献类型:
--
作者:
R. Amarnath;C. Berseth;J. Malagelada;J. Perrault;T. Abell;A. D. Hoffman

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采用灌注测压法研究15例早产儿和足月儿肠内喂养开始前小肠运动的成熟情况(研究1);11名早产儿中有7名在肠内喂养3周或更长时间后被重新研究(研究2)。在研究1中,四个足月婴儿的消化间运动表现出静止和节律性活动的周期,与在成人中观察到的定期迁移运动复合物相一致;进食后,运动变化为不规则的阶段性活动。然而,早产儿在禁食期间仅表现出无组织的阶段性活动簇,并且对喂养没有一致的运动反应模式。在肠内喂养3周或更长时间后,出现了带有迁移运动复合物的消化间循环,以及对喂养的一致、明显的运动反应。在研究2中,孕32周的早产儿表现出“成熟”的运动模式,结果表明肠道运动随着受孕后年龄的增长而成熟。
Perfusion manometry was used to study the maturation of small intestinal motility in 15 preterm and term infants before the initiation of enteral feeding (study 1); seven of the 11 preterm infants were restudied after 3 weeks or more of enteral feeding (study 2). During study 1, the interdigestive motility of the four term infants exhibited cycles of quiescence and rhythmic activity, compatible with migrating motor complexes observed regularly in adults; in response to feeding, motility changed to irregular, phasic activity. Preterm infants, however, showed only unorganized clusters of phasic activity during fasting, and there was no consistent pattern of motor response to feeding. After 3 or more weeks of enteral feeding, interdigestive cycles with migratory motor complexes and a consistent, obvious motor response to feeding were present. Preterm infants as young as 32 weeks' gestation showed “mature” motor patterns in study 2, results suggesting that intestinal motility matures with postconceptual age.
DOI: --
发表时间: 1986
期刊: Pediatrics
影响因子: 8
作者:
MorrissJr,FH;Moore,M;Weisbrodt,NW;West,MS
通讯作者: West,MS