EFFERENT CORTICAL CONNECTIONS OF MULTIMODAL CORTEX OF THE SUPERIOR TEMPORAL SULCUS IN THE RHESUS-MONKEY
EFFERENT CORTICAL CONNECTIONS OF MULTIMODAL CORTEX OF THE SUPERIOR TEMPORAL SULCUS IN THE RHESUS-MONKEY
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DOI：
10.1002/cne.903180207
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发表时间：
1992-04-08
影响因子：
2.5
通讯作者：
PANDYA, DN
中科院分区：
文献类型：
--
作者：
BARNES, CL;PANDYA, DN
恒河猴颞上沟(STS)上岸的皮质包含一个接受罗兰迪克后感觉联结区的重叠输入的区域，被认为是本质上的多模式。我们使用了荧光逆行追踪技术来回答STS的多模式区域是否投射回后罗兰德感觉关联区的问题。此外，我们还试图回答这样一个问题，即从多模式区到感觉副联结区的投射是通过轴突侧支来自普通神经元还是来自个别神经元。结果表明，STS的多模区TPO投射回顶叶(躯体感觉)、颞上回(听觉)和海马旁后回(视觉)的特定单峰副感觉联结区。此外，TPO区的大量投射投射到远端感觉副联结区、顶下小叶的PG-OPT区、颞上回的Ts1区和Ts2区，以及海马旁回的Tf区和Tl区。后一类区域本身就被认为是较高级别的关联区。还注意到，对这些高级别联结区的大多数投影来自TPO区(TPO-2和TPO-3)的中间分区。这些神经元以显著重叠的方式组织起来。尽管有这种投射神经元的重叠，但在TPO区只观察到偶尔的双标记神经元。因此，我们的观察表明，颞上沟的多通道区域与服务于躯体感觉、听觉和视觉通道的单峰副感觉联结皮质以及其他后罗兰德时期的高阶联结区域具有相互联系。这些从TPO区到罗兰德后联结区的联系可能对感觉联结输入产生调制影响，从而导致颞上沟区的多模区。
The cortex of the upper bank of the superior temporal sulcus (STS) in the rhesus monkey contains a region that receives overlapping input from post-Rolandic sensory association areas and is considered multimodal in nature. We have used the fluorescence retrograde tracing technique in order to answer the question of whether multimodal areas of the STS project back to post-Rolandic sensory association areas. Additionally, we have attempted to answer the question of whether the projections from the multimodal areas directed to the parasensory association areas originate from common neurons via axon collaterals or from individual neurons. The results show that multimodal area TPO of the STS projects back to specific unimodal parasensory association areas of the parietal lobe (somatosensory), superior temporal gyrus (auditory), and posterior parahippocampal gyrus (visual). In addition, a substantial number of projections from area TPO are directed to distal parasensory association areas, area PG-Opt in the inferior parietal lobule, areas Ts1 and Ts2 in the rostral superior temporal gyrus, and areas TF and TL in the parahippocampal gyrus. These latter regions are themselves considered to be higher-order association areas. It was also noted that the majority of the projections to these higher-order association areas originate from the middle divisions of area TPO (TPO-2 and TPO-3). These neurons are organized in a significantly overlapping manner. Despite this overlap of the projection neurons, only an occasional double labeled neuron was observed in area TPO. Thus, our observations indicate that the multimodal region of the superior temporal sulcus has reciprocal connections with the unimodal parasensory association cortices subserving somatosensory, auditory and visual modalities, as well as with other post-Rolandic higher-order association areas. These connections from area TPO to post-Rolandic association areas may have a modulating influence on the sensory association input leading to multimodal areas in the superior temporal sulcus.