Patternhunter II: highly sensitive and fast homology search.
Patternhunter II: highly sensitive and fast homology search.
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DOI：
10.1142/s0219720004000661
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发表时间：
2004-09-01
影响因子：
1
通讯作者：
Tromp, John
中科院分区：
文献类型：
--
作者：
Li, Ming;Ma, Bin;Tromp, John
PatternHunter II将PatternHunter(20)的单个优化间隔种子扩展到多个种子，同时弥补了Blastn算法对同源搜索的敏感度和Smith-Waterman算法速度的不足。以Blastn的速度，PatternHunter II接近史密斯-沃特曼的敏感度，使同源搜索方法论研究回到了一个完整的循环。
Extending the single optimized spaced seed of PatternHunter(20) to multiple ones, PatternHunter II simultaneously remedies the lack of sensitivity of Blastn and the lack of speed of Smith-Waterman, for homology search. At Blastn speed, PatternHunter II approaches Smith-Waterman sensitivity, bringing homology search methodology research back to a full circle.