Mental burden and its risk and protective factors during the early phase of the SARS-CoV-2 pandemic: systematic review and meta-analyses.
Mental burden and its risk and protective factors during the early phase of the SARS-CoV-2 pandemic: systematic review and meta-analyses.
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DOI：
10.1186/s12992-021-00670-y
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发表时间：
2021-03-29
影响因子：
10.8
通讯作者：
Lieb K
中科院分区：
文献类型：
--
作者：
Kunzler AM;Röthke N;Günthner L;Stoffers-Winterling J;Tüscher O;Coenen M;Rehfuess E;Schwarzer G;Binder H;Schmucker C;Meerpohl JJ;Lieb K
由于SARS-CoV-2大流行而造成的精神负担已被广泛报道，适用于普通公众和特定风险群体，如医护人员和不同的患者群体。我们的目标是通过比较大流行与大流行前的数据来评估其对早期心理健康的影响，并确定潜在的风险和保护因素。对于本系统综述和荟萃分析，我们系统检索了PubMed、PsycINFO和Web of Science，检索时间为2019年1月1日至2020年5月29日，并筛选了纳入研究的参考文献列表。此外，我们还检索了PubMed和PsycINFO，以获得大流行前的比较数据。纳入了评估SARS-CoV-2大流行在普通人群、医护人员或任何患者（如COVID-19患者）中造成的精神负担的调查研究，这些研究具有广泛的合格精神健康结局，以及评估相同人群中大流行前比较数据的匹配研究（如可用）。我们使用多水平荟萃分析进行主要、亚组和敏感性分析，重点关注（感知）压力、焦虑和抑郁症状以及睡眠相关症状作为主要结局。在检索到的2429条记录中，104条被纳入综述（n = 208，261例受试者），43条被纳入荟萃分析（n = 71，613例受试者）。虽然焦虑的症状与大流行前相比，在大流行早期，一般人群的精神疾病（标准化均值差[SMD] 0.40; 95%CI 0.15-0.65）和抑郁症（SMD 0.67; 95%CI 0.07-1.27）增加，但无论是否接触过COVID-19患者，患者和医护人员的精神负担都没有增加。特定结局指标（如患者健康问卷）和较旧的比较数据（≥5年前发表）与精神负担增加相关。在这三个人群中，现有的精神障碍，女性性别和对感染的担忧被反复报告为风险因素，而年龄较大，良好的经济状况和教育是保护因素。与以往的综述相比，本次荟萃分析描绘了大流行情况下心理健康后果的差异化图景。需要高质量的、有代表性的调查、高粒度的纵向研究以及更多关于保护因素的研究，以更好地了解SARS-CoV-2大流行的心理影响，并帮助设计针对特定人群需求的有效预防措施和干预措施。在线版本包含补充材料，可通过10.1186/s12992-021-00670-y获得。
Mental burden due to the SARS-CoV-2 pandemic has been widely reported for the general public and specific risk groups like healthcare workers and different patient populations. We aimed to assess its impact on mental health during the early phase by comparing pandemic with prepandemic data and to identify potential risk and protective factors. For this systematic review and meta-analyses, we systematically searched PubMed, PsycINFO, and Web of Science from January 1, 2019 to May 29, 2020, and screened reference lists of included studies. In addition, we searched PubMed and PsycINFO for prepandemic comparative data. Survey studies assessing mental burden by the SARS-CoV-2 pandemic in the general population, healthcare workers, or any patients (eg, COVID-19 patients), with a broad range of eligible mental health outcomes, and matching studies evaluating prepandemic comparative data in the same population (if available) were included. We used multilevel meta-analyses for main, subgroup, and sensitivity analyses, focusing on (perceived) stress, symptoms of anxiety and depression, and sleep-related symptoms as primary outcomes. Of 2429 records retrieved, 104 were included in the review (n = 208,261 participants), 43 in the meta-analysis (n = 71,613 participants). While symptoms of anxiety (standardized mean difference [SMD] 0.40; 95% CI 0.15–0.65) and depression (SMD 0.67; 95% CI 0.07–1.27) were increased in the general population during the early phase of the pandemic compared with prepandemic conditions, mental burden was not increased in patients as well as healthcare workers, irrespective of COVID-19 patient contact. Specific outcome measures (eg, Patient Health Questionnaire) and older comparative data (published ≥5 years ago) were associated with increased mental burden. Across the three population groups, existing mental disorders, female sex, and concerns about getting infected were repeatedly reported as risk factors, while older age, a good economic situation, and education were protective. This meta-analysis paints a more differentiated picture of the mental health consequences in pandemic situations than previous reviews. High-quality, representative surveys, high granular longitudinal studies, and more research on protective factors are required to better understand the psychological impacts of the SARS-CoV-2 pandemic and to help design effective preventive measures and interventions that are tailored to the needs of specific population groups. The online version contains supplementary material available at 10.1186/s12992-021-00670-y.
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DOI：
10.23750/abm.v91i2.9619
发表时间：
2020-05-11
期刊：
Acta bio-medica : Atenei Parmensis
影响因子：
--
作者：
Amerio A;Bianchi D;Santi F;Costantini L;Odone A;Signorelli C;Costanza A;Serafini G;Amore M;Aguglia A
通讯作者：
Aguglia A
影响因子：
11.3
作者：
Cao, Wenjun;Fang, Ziwei;Zheng, Jianzhong
通讯作者：
Zheng, Jianzhong
影响因子：
2
作者：
Alosaimi, Fahad D.;Alawad, Hossam S.;Alfaris, Eiad A.
通讯作者：
Alfaris, Eiad A.
影响因子：
3.4
作者：
Bonfiglio, Natale Salvatore;Renati, Roberta;Friborg, Oddgeir
通讯作者：
Friborg, Oddgeir
影响因子：
1.1
作者：
Bilgel, Nazan;Bayram, Nuran
通讯作者：
Bayram, Nuran