NOVEL CLOSED-CIRCULAR MITOCHONDRIAL DNA WITH PROPERTIES OF A REPLICATING INTERMEDIATE

NOVEL CLOSED-CIRCULAR MITOCHONDRIAL DNA WITH PROPERTIES OF A REPLICATING INTERMEDIATE
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DOI:
10.1073/pnas.68.9.2252
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发表时间:
1971-01-01
影响因子:
11.1
通讯作者:
VINOGRAD, J
VINOGRAD, J
中科院分区:
综合性期刊1区
文献类型:
--
作者:
KASAMATSU, H;ROBBERSON, DL;VINOGRAD, J

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小鼠L细胞中部分共价闭合的线粒体DNA包含一个复制的重链片段,该片段与环状轻链氢键相连。插入的单链在高温下可从环形双链上解离。
A fraction of the covalently closed mitochondrial DNA in mouse L cells contains a replicated heavy-strand segment that is hydrogen bonded to the circular light strand. The inserted single strand is dissociable from the circular duplex at an elevated temperature.