Handheld rectilinear ion trap mass spectrometer
Handheld rectilinear ion trap mass spectrometer
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DOI：
10.1021/ac061144k
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发表时间：
2006-09-01
影响因子：
7.4
通讯作者：
Ouyang, Zheng
中科院分区：
文献类型：
--
作者：
Gao, Liang;Song, Qingyu;Ouyang, Zheng
一个鞋盒大小，10公斤，手持质谱仪，迷你10，直线离子阱质量分析仪的基础上，已设计，建造，和特点。该仪器是在质谱仪小型化方面长达十年的实验和模拟计划的基础上发展起来的。直线型离子阱具有简化的几何形状和高捕获能力，当与微型和坚固的泵送系统一起使用时，它允许在携带仪器的同时进行化学分析。开发了紧凑的电子设备，包括空芯RF驱动线圈，以控制仪器并记录质谱。该仪器使用电池供电，功耗低于70 W，与笔记本电脑相似。实现了有线和无线联网功能。仪器给出单位分辨率和超过m/z 500的质量范围。串联质谱能力是使用碰撞诱导解离实现的，它们用于在原位分析期间提供化学结构的确认。空气和溶液样品的连续监测证明，并获得了50 ppb的检测限为甲苯蒸气在空气中，并为萘水溶液使用膜样品引入。
A shoebox- sized, 10-kg, handheld mass spectrometer, Mini 10, based on a rectilinear ion trap mass analyzer has been designed, built, and characterized. This instrument has evolved from a decade-long experimental and simulation program in mass spectrometer miniaturization. The rectilinear ion trap has a simplified geometry and high trapping capacity, and when used with a miniature and ruggedized pumping system, it allows chemical analysis while the instrument is being carried. Compact electronics, including an air core RF drive coil, were developed to control the instrument and to record mass spectra. The instrument runs on battery power, consuming less than 70 W, similar to a laptop computer. Wired and wireless networking capabilities are implemented. The instrument gives unit resolution and a mass range of over m/z 500. Tandem mass spectrometry capabilities are implemented using collision-induced dissociation, and they are used to provide confirmation of chemical structure during in situ analysis. Continuous monitoring of air and solution samples is demonstrated, and a limit of detection of 50 ppb was obtained for toluene vapor in air and for an aqueous naphthalene solution using membrane sample introduction.