Effect of intranasal oxygen administration on blood gas variables and outcome in neonatal calves with respiratory distress syndrome:: 20 cases (2004-2006)
Effect of intranasal oxygen administration on blood gas variables and outcome in neonatal calves with respiratory distress syndrome:: 20 cases (2004-2006)
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DOI：
10.2460/javma.233.2.289
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发表时间：
2008-07-15
影响因子：
1.9
通讯作者：
Kaehn, Wolfgang K.
中科院分区：
文献类型：
--
作者：
Bleul, Ulrich T.;Bircher, Barbara M.;Kaehn, Wolfgang K.
目的-确定鼻内给氧对新生小牛呼吸窘迫综合征（RDS）血气变量和结果的影响。设计-回顾性病例系列。动物-20头新生小牛RDS。程序-动脉氧分压（Pao（2）），动脉二氧化碳分压，结果鼻内给氧后PaO 2、SaO 2明显升高，SaO 2明显升高，SaO 2明显升高。开始给氧后的前24小时内，在治疗的前3小时内，平均+/- SD Pao（2）从38.4 +/- 8.8 mm Hg增加到58.7 +/- 178 mm Hg。开始给氧后12小时内Pao（2）> 55 mm Hg的犊牛的存活率（9/10）显著高于未达到此阈值的犊牛（4/10）。结论和临床相关性-结果表明鼻内给氧是改善新生儿RDS犊牛血气指标的简单方法，Pao（2）可以用来预测结果。
Objective-To determine the effect of intranasal oxygen administration on blood gas variables and outcome in neonatal calves with respiratory distress syndrome (RDS).Design-Retrospective case series.Animals-20 neonatal calves with RDS.Procedures-Arterial partial pressure of oxygen (Pao(2)), arterial partial pressure of carbon dioxide, and arterial oxygen saturation (Sao(2)) before and after intranasal administration of oxygen were analyzed.Results-There were significant increases in PaO2 and Sao(2) in the first 24 hours after oxygen administration was begun, with mean +/- SD Pao(2) increasing from 38.4 +/- 8.8 mm Hg to 58.7 +/- 178 mm Hg during the first 3 hours of treatment. Calves with Pao(2) > 55 mm Hg within the first 12 hours after oxygen administration was begun had a significantly higher survival rate (9/10) than did calves that did not reach this threshold (4/10).Conclusions and Clinical Relevance-Results suggested that intranasal oxygen administration was a simple method of improving blood gas variables in neonatal calves with RDS and that Pao(2) could be used to predict outcome.