Developmental HSC Microenvironments: Lessons from Zebrafish.
Developmental HSC Microenvironments: Lessons from Zebrafish.
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DOI：
10.1007/978-3-319-69194-7_4
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发表时间：
2017
影响因子：
--
通讯作者：
Bowman TV
中科院分区：
文献类型：
--
作者：
Nik S;Weinreb JT;Bowman TV
Hematopoietic stem cells (HSCs) posses the ability to maintain the blood system of an organism from birth to adulthood. The behavior of HSCs is modulated by its microenvironment. During development, HSCs acquire the instructions to self-renew and differentiate into all blood cell fates by passing through several developmental microenvironments. In this chapter, we discuss the signals and cell types that inform HSC decisions throughout ontogeny with a focus on HSC specification, mobilization, migration, and engraftment.
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