MR angiography with sensitivity encoding (SENSE) for suspected pulmonary embolism: Comparison with MDCT and ventilation-perfusion scintigraphy
MR angiography with sensitivity encoding (SENSE) for suspected pulmonary embolism: Comparison with MDCT and ventilation-perfusion scintigraphy
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DOI：
10.2214/ajr.183.1.1830091
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发表时间：
2004-07-01
影响因子：
5
通讯作者：
Sugimura, K
中科院分区：
文献类型：
--
作者：
Ohno, Y;Higashino, T;Sugimura, K
OBJECTIVE.本研究的目的是确定时间分辨对比增强磁共振血管造影结合灵敏度编码（SENSE）对肺栓塞患者的实用性。48例疑似肺栓塞的连续患者（26例男性和22例女性;年龄范围：27-73岁;平均年龄：55岁）接受了胸部X线摄影、对比增强MDCT、使用SENSE的MR血管造影、通气-灌注动脉造影和肺动脉造影。在1.5-T扫描仪上，使用静脉注射钆对比剂和3D快速场回波脉冲序列（TR/TE，4.0/1.2;翻转角，30度）进行SENSE MR血管造影。以肺动脉造影结果为参考标准，通过受试者操作特征分析确定使用MR血管造影（数据集A）、对比增强MD（数据集B）、对比增强MDCT与MR血管造影（数据集C）、通气-灌注肺动脉造影（数据集D）和对比增强MDCT与通气-灌注肺动脉造影（数据集E）诊断肺栓塞的能力。采用McNemar检验，在每血管区域和每患者基础上分析每个数据集的诊断能力。数据集A的灵敏度和特异性分别为83%和97%，基于每血管区域，92%和94%，基于每患者。在每个患者的基础上，数据集A的特异性和准确性显著高于数据集D（p < 0.05）。SENSE时间分辨MR血管成像是诊断肺栓塞的有效方法。
OBJECTIVE. The aim of our study was to determine the utility of time-resolved contrast-enhanced MR angiography combined with sensitivity encoding (SENSE) for patients with pulmonary embolism.SUBJECTS AND METHODS. Forty-eight consecutive patients (26 men and 22 women; age range, 27-73 years; mean age, 55 years) with suspected pulmonary embolism underwent chest radiography, contrast-enhanced MDCT, MR angiography with SENSE, ventilation-perfusion scintigraphy, and pulmonary angiography. MR angiography with SENSE was performed using IV administration of gadolinium contrast medium with a 3D turbo field-echo pulse sequence (TR/TE, 4.0/1.2; flip angle, 30degrees) on a 1.5-T scanner. Capabilities of diagnosing pulmonary embolism using MR angiography (data set A), contrast-enhanced MD (data set B), contrast-enhanced MDCT with MR angiography (data set C), ventilation-perfusion scintigraphy (data set D), and contrast-enhanced MDCT with ventilation-perfusion scintigraphy (data set E) were determined by receiver operating characteristic analysis, using the results of pulmonary angiography as the reference standard. The diagnostic capability of each data set was analyzed on a per-vascular zone and a per-patient basis with the McNemar test.RESULTS. Sensitivity and specificity of data set A were 83% and 97%, respectively, on a per-vascular zone basis and 92% and 94%, respectively, on a per-patient basis. Specificity and accuracy of data set A were significantly higher than those of data set D on a per-patient basis (p < 0.05).CONCLUSION. Time-resolved MR angiography with SENSE is effective for the diagnosis of pulmonary embolism.