New genetic and proteomic discoveries and recent insights into the risk factors and pathophysiology of how pseudoexfoliation glaucoma develops. Preface.
New genetic and proteomic discoveries and recent insights into the risk factors and pathophysiology of how pseudoexfoliation glaucoma develops. Preface.
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新的遗传和蛋白质组学发现以及对假性剥脱性青光眼如何发展的危险因素和病理生理学的最新见解。
DOI：
10.1097/iio.0000000000000046
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发表时间：
2014
影响因子：
--
通讯作者：
Lee,RichardK
中科院分区：
文献类型：
--
作者：
Lee,RichardK
佛罗里达州迈阿密迈阿密大学米勒医学院巴斯科姆·帕尔默眼科研究所眼科学、细胞生物学和神经科学副教授，佛罗里达州33136开角型青光眼(OAG)是一种青光眼家族，通常在裂隙灯下表现出明显的临床特征。原发性开角型青光眼(POAG)是最常见的青光眼类型之一，但POAG是一种排除诊断。POAG的诊断假定未发现继发性青光眼，即假性剥脱性青光眼、色素性青光眼、新生血管性青光眼或虹膜角膜青光眼。假性剥脱性青光眼是世界上最常见的继发性OAG。假性剥脱性青光眼的诊断是在前房的前段出现一种典型的白色头皮屑样物质。自从Lindberg在近一百年前正式描述假剥落以来，伪剥落物质的组成和如何导致青光眼仍然不是很清楚。
Associate Professor of Ophthalmology, Cell Biology, and Neuroscience, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL 33136Open angle glaucoma (OAG) is a family of glaucomas that are differentiated by clinical features usually apparent at the slit lamp. Primary open angle glaucoma (POAG) is one of the most commonly diagnosed types of glaucoma but POAG is a diagnosis of exclusion. A diagnosis of POAG presumes that no secondary form of glaucoma has been identified ie pseudoexfoliation glaucoma, pigmentary glaucoma, neovascular glaucoma, or iridocorneal glaucoma. Pseudoexfoliation glaucoma is the most commonly identified secondary OAG in the world. Pseudoexfoliation glaucoma is diagnosed by the presence of a characteristic white dandruff-like material in the anterior segment in the anterior chamber in the eye. Since the formal description of pseudoexfoliation by Lindberg almost a hundred years ago, the composition of the pseudoexfoliation material and how pseudoexfoliation material causes glaucoma is still not well known.