The prevalence of hypopharynx findings associated with gastroesophageal reflux in normal volunteers
The prevalence of hypopharynx findings associated with gastroesophageal reflux in normal volunteers
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DOI：
10.1016/s0892-1997(02)00132-7
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发表时间：
2002-12-01
期刊：
影响因子：
2.2
通讯作者：
Richter, JE
中科院分区：
文献类型：
--
作者：
Hicks, DM;Ours, TM;Richter, JE
耳鼻喉科主诉患者的常规喉部检查常发现胃食管反流的结果。这些粘膜发现和不受控制的反流之间的直接联系尚未明确。为了开始探索组织体征的特异性，对105名正常、健康的成年志愿者进行了常规视频光纤内窥镜检查，以确定是否存在归因于反流病的结果。调查医疗条件、生活方式因素和耳鼻喉科投诉，以揭示潜在的气道刺激物，同时研究设计试图消除无症状反流。大多数受试者（86%）的结果与反流相关，某些体征的患病率达到70%。耳鼻喉科主诉、吸烟、饮酒或哮喘不影响患病率。提供检查者内和检查者间一致性信息。下咽部刺激体征返流的传统属性受到挑战，需要提高诊断特异性的突出。
Routine laryngeal examination of patients with otolaryngologic complaints often reveals findings thought to result from gastroesophageal reflux. The direct association between these mucosal findings and uncontrolled reflux is not well established. To begin exploring the specificity of tissue signs, 105 normal, healthy, adult volunteers were examined by routine video fiber-optic endoscopy for the presence of findings attributed to reflux disease. Medical conditions, lifestyle factors, and ENT complaints were surveyed to reveal potential airway irritants, while the study design attempted to eliminate silent reflux. The majority of subjects (86%) had findings associated with reflux and certain signs reached a prevalence of 70%. Prevalence was not affected by ENT complaint, smoking, alcohol, or asthma. Intraexaminer and interexaminer agreement information is provided. The traditional attribution of hypopharynx irritation signs to reflux is challenged; the need for improved diagnostic specificity is highlighted.