A two-way messaging system to enhance antiretroviral adherence
A two-way messaging system to enhance antiretroviral adherence
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DOI：
10.1197/jamia.m1047
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发表时间：
2003-01-01
影响因子：
6.4
通讯作者：
Hooton, TM
中科院分区：
文献类型：
--
作者：
Dunbar, PJ;Madigan, D;Hooton, TM
未能坚持复杂的抗逆转录病毒治疗方案可能会导致艾滋病毒阳性者产生耐药性和治疗失败。在这项关于自动双向消息系统提高依从性的可行性的研究中，参与者收到了多条每日简短消息，旨在提醒、教育、鼓励依从性，并征求有关副作用和自我报告依从性的回应。 25 名参与者参与研究的平均时间为 208 天，收到了 17,440 条消息并回复了 14,677 条消息（84%）。参与者在 743 次询问中，有 36% 报告缺少一剂或多剂，在 729 次询问中，有 26% 报告了药物副作用。参与者对消息系统表示高度满意，并报告说它有助于提高用药依从性。该研究表明，使用自动无线双向消息系统与艾滋病毒阳性患者进行长时间沟通是可行的。
Failure to adhere to complex antiretroviral regimens can lead to resistance and treatment failure among HIV-positive persons. In this study of the feasibility of an automated two-way messaging system to improve adherence, participants received multiple short daily messages designed to remind, educate, encourage adherence, and solicit responses concerning side effects and self-reported adherence. Twenty-five participants remained in the study for a median of 208 days, receiving 17,440 messages and replying to 14,677 (84%). Participants reported missing one or more doses on 36% of 743 queries and reported medication side effects on 26% of 729 queries. Participants expressed high satisfaction with the messaging system and reported that it helped with medication adherence. The study suggests that it is feasible to use an automated wireless two-way messaging system to communicate with HIV-positive patients over an extended period of time.