PHOTORECEPTOR OUTER SEGMENTS - ACCELERATED MEMBRANE RENEWAL IN RODS AFTER EXPOSURE TO LIGHT
PHOTORECEPTOR OUTER SEGMENTS - ACCELERATED MEMBRANE RENEWAL IN RODS AFTER EXPOSURE TO LIGHT
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DOI：
10.1126/science.300504
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发表时间：
1977-01-01
期刊：
影响因子：
56.9
通讯作者：
RAYBORN, ME
中科院分区：
文献类型：
--
作者：
BESHARSE, JC;HOLLYFIELD, JG;RAYBORN, ME
在恒光和12或2小时光照/天的条件下，林蛙蝌蚪的杆状外节更新率显著高于黑暗中的动物。光照24小时，黑暗6天后，更新率是黑暗的3-4倍。非洲爪哇蝌蚪在正常昼夜周期的前8h的更新速率是随后16h的5倍以上，更新活动的爆发显然是对光的反应，光与暗交替的正常模式可能在杆状外节翻转的调节中起基本作用。
The rate of rod outer segment renewed in Rana pipiens tadpoles under constant light and under diurnal conditions of 12 or 2 h light/day was significantly increased compared to that in animals in darkness. During 24 h in light after 6 days in darkness the rate of renewal was 3-4 times that in darkness. In Xenopus laevis tadpoles the rate of renewal was more than 5 times greater during the first 8 h of a normal diurnal cycle than during the following 16 h. Apparently bursts of renewal activity occur as a response to light, and a normal pattern of light alternating with darkness may play a fundamental role in the regulation of rod outer segment turnover.