Adiposity rebound is misclassified by BMI rebound
Adiposity rebound is misclassified by BMI rebound
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DOI：
10.1038/ejcn.2013.131
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发表时间：
2013-09-01
影响因子：
4.7
通讯作者：
Mueller, M. J.
中科院分区：
文献类型：
--
作者：
Plachta-Danielzik, S.;Bosy-Westphal, A.;Mueller, M. J.
背景/目的：肥胖反弹是指3~7岁儿童体重指数(BMI)百分位数的最低点或拐点。早期反弹被视为肥胖的风险，因此，AR被认为是预防的合适时间段。由于BMI不能反映身体成分，我们的目标是与BMI一起检查脂肪质量指数(FMI)和脱脂质量指数(FFMI)的反弹。SUBJECTS/方法：19264名3-11岁儿童的横断面数据来自三项德国研究(基尔肥胖预防研究，该项目名为“更好的饮食。更多锻炼。KINDERLEICHT-Regions”和对耶拿儿童的定期检查)。测量身高和体重。通过生物电阻抗分析获得脂肪质量(FM)和脱脂质量(FFM)，并使用群体特异性算法进行分析。结果：BMI、FMI、FMI百分位数均随年龄增长呈回升趋势，而FFMI百分位数随年龄增长呈稳步上升趋势。在P90阶段，FMI的反弹比BMI晚1.6-1.8岁，即男孩4.2岁(BMI)和5.8岁(FMI)，女孩4.2岁(BMI)和6.0岁(FMI)。在AR，BMI-P90的斜率是由FFMI的增加而不是FMI的增加来解释的。相反，在FMI反弹时，BMI的斜率与FMI密切相关。结论：BMI反弹不等于FM的反弹。在AR中，BMI的斜率由FFMI的增加决定。AR应该被定义为FMI反弹，而不是BMI反弹。
BACKGROUND/OBJECTIVES: Adiposity rebound (AR) is defined as the nadir or the inflexion point of body mass index (BMI) percentiles between the age of 3 and 7 years. An early rebound is seen as a risk of obesity and, thus, AR is considered as a suitable time period for prevention. As BMI does not reflect body composition, we aimed to examine the rebounds of fat mass index (FMI) and fat-free mass index (FFMI) together with BMI.SUBJECTS/METHODS: Cross-sectional data of 19 264 children aged 3-11 years were pooled from three German studies (Kiel Obesity Prevention Study, the project 'Better diet. More exercise. KINDERLEICHT-REGIONS' and regular examinations of Jena children). Height and weight were measured. Fat mass (FM) and fat-free mass (FFM) were obtained from bioelectrical impedance analysis and analysed using a population-specific algorithm. Percentiles of BMI, FMI and FFMI were constructed by the LMS method.RESULTS: Both BMI and FMI percentiles showed a rebound, whereas FFMI percentiles steadily increased with age. On P90, FMI rebound was about 1.6-1.8 years later compared with that of BMI, that is, at ages 4.2 years (BMI) and 5.8 years (FMI) in boys and at 4.2 years (BMI) and 6.0 years (FMI) in girls. At AR, the slope of the BMI-P90 was explained by increases in FFMI rather than FMI. By contrast, at FMI rebound, the slope of BMI was strongly related to FMI.CONCLUSIONS: BMI rebound does not equal the rebound of FM. At AR, the slope in BMI is determined by the increase in FFMI. AR should be defined as FMI rebound rather than BMI rebound.