Non-medical use of prescription opioids during the transition to adulthood: a multi-cohort national longitudinal study

Non-medical use of prescription opioids during the transition to adulthood: a multi-cohort national longitudinal study
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DOI:
10.1111/add.12347
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发表时间:
2014-01-01
期刊:
影响因子:
6
通讯作者:
Kloska, Deborah D.
Kloska, Deborah D.
中科院分区:
医学1区
文献类型:
--
作者:
McCabe, Sean Esteban;Schulenberg, John E.;Kloska, Deborah D.

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目的研究从青春期到成年期的过渡期间处方阿片类药物(NMUPO)的非医疗使用模式,并评估与NMUPO纵向模式相关的个体特征和其他物质使用行为。(波1:模态年龄18岁)在三个两年期随访波中纵向随访(第2、3和4波:正常年龄19/20,21/22和23/24岁)。设置数据收集通过自填问卷的高中毕业生和年轻人。(高中高年级1976-2005)who participated in all four waves.MeasurementsSelf-reports of NMUPO and other substance use behaviors.FindingsApproximately 11.6% [95% confidence interval(CI)= 11.2%,12.0%] of the sample reported past year NMUPO in at least one of the four waves.在报告去年NMUPO至少为一个波的患者中,分别有69.0%(67.6%,70.4%)、20.5%(19.3%,21.7%)、7.8%(7.1%,8.6%)和2.7%(2.3%,3.1%)报告NMUPO为一个、两个、三个和四个波。几个波1变量与NMUPO的多个波的更大的几率相关,并且报告NMUPO的更多波的个体具有更大的其他物质使用behaviors.ConclusionsAlthough大多数非医疗使用处方阿片类药物在18岁的美国人中似乎是不连续的,报告非医疗使用处方阿片类药物的样本中约有三分之一似乎在18岁以后继续使用,并且在23岁时其他物质使用行为的几率增加。24.
AimsTo examine non-medical use of prescription opioids (NMUPO) patterns during the transition from adolescence to adulthood, and assess individual characteristics and other substance use behaviors associated with longitudinal patterns of NMUPO.DesignNationally representative samples of high school seniors in the United States (wave 1: modal age 18 years) were followed longitudinally across three biennial follow-up waves (waves 2, 3 and 4: modal ages 19/20, 21/22 and 23/24 years).SettingData were collected via self-administered questionnaires to high school seniors and young adults.ParticipantsThe longitudinal sample consisted of 27268 individuals in 30 cohorts (high school senior years 1976-2005) who participated in all four waves.MeasurementsSelf-reports of NMUPO and other substance use behaviors.FindingsApproximately 11.6% [95% confidence interval (CI)=11.2%, 12.0%] of the sample reported past-year NMUPO in at least one of the four waves. Among those who reported past-year NMUPO in at least one wave, 69.0% (67.6%, 70.4%), 20.5% (19.3%, 21.7%), 7.8% (7.1%, 8.6%) and 2.7% (2.3%, 3.1%) reported NMUPO at one, two, three and four waves, respectively. Several wave 1 variables were associated with greater odds of multiple waves of NMUPO and individuals who reported more waves of NMUPO had greater odds of other substance use behaviors.ConclusionsAlthough most non-medical use of prescription opioids among 18-year-olds in the United States appears to be non-continuing, approximately one-third of the sample reporting non-medical use of prescription opioids appear to continue use beyond age 18 and have elevated odds of other substance use behaviors at ages 23/24.