Primer on medical Genomics Part VII: The evolving concept of the gene
Primer on medical Genomics Part VII: The evolving concept of the gene
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DOI：
10.4065/78.5.580
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发表时间：
2003-05-01
影响因子：
8.9
通讯作者：
Wieben, ED
中科院分区：
文献类型：
--
作者：
Wieben, ED
人类基因组序列草案已于两年前报道，填补空白和完善序列的任务已接近完成。然而，尽管取得了这一非凡成就，但仍然没有对人类基因组中包含的基因数量进行明确的评估。在某种程度上，这种不确定性反映了我们对基因结构的复杂性和多样性的日益了解。在讨论我们对基因结构和功能的理解的演变的背景下，考虑了复杂基因结构的例子。
The draft sequence of the human genome was reported 2 years ago, and the task of filling gaps and polishing the sequence is nearing completion. However, despite this remarkable achievement, there is still no definitive assessment of the number of genes contained in the human genome. In part, this uncertainty reflects our growing understanding of the complexity and diversity of gene structure. Examples of complex gene structure are considered in the context of a discussion about the evolution of our understanding of gene structure and function.