Diffuse FDG uptake in the bilateral lungs: hypersensitivity pneumonitis supported by low-dose CT findings.
Diffuse FDG uptake in the bilateral lungs: hypersensitivity pneumonitis supported by low-dose CT findings.
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DOI：
10.22038/aojnmb.2021.56000.1393
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发表时间：
2022
影响因子：
--
通讯作者：
Kuji I
中科院分区：
文献类型：
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作者：
Goto S;Matsusaka Y;Yamane T;Hoshino Y;Kuji I
过敏性肺炎（HP）是一种间质性肺病，由易感和致敏个体对环境中各种吸入抗原的免疫介导反应引起。影像学诊断通常基于高分辨率CT表现。在此，我们报告一位49岁男性，有弥漫性大B细胞淋巴瘤病史，表现为发烧和偶尔咳嗽。18F-氟脱氧葡萄糖（FDG）正电子发射断层扫描/计算机断层扫描（PET/CT）显示双侧肺弥漫性FDG摄取。呼气相低剂量CT同时进行PET扫描显示小叶中心结节和空气滞留在毛玻璃影（GGO）。我们的影像学诊断是急性过敏性肺炎（HP）。根据他的临床病程、血液实验室检查和支气管镜检查结果，他被诊断为急性HP。急性HP患者肺组织FDG弥漫性摄取。此外，呼气低剂量CT显示小叶中心结节和GGO中的空气滞留可能有助于急性HP的准确诊断。
Hypersensitivity pneumonitis (HP) is an interstitial lung disease resulting from an immune-mediated response in susceptible and sensitized individuals to various inhaled antigens in the environment. Imaging diagnosis is usually based on high-resolution CT findings. Here, we present a 49-year-old man with a history of diffuse large B-cell lymphoma presented with fever and occasional cough. 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) revealed diffuse FDG uptake in the bilateral lungs. Expiratory low-dose CT simultaneously performed in PET scanning revealed centrilobular nodules and air trapping in ground glass opacities (GGO). Our imaging diagnosis was acute hypersensitivity pneumonitis (HP). Based on the results of his clinical course, blood laboratory tests, and bronchoscopy, he was diagnosed with acute HP. Diffuse pulmonary FDG uptake can be seen in the patients with acute HP. In addition, expiratory low-dose CT findings of centrilobular nodules and air trapping in GGO may be helpful for accurate diagnosis of acute HP.