Integrating the Xpert MTB/RIF Assay into a Diagnostic Workflow for Rapid Detection of Mycobacterium tuberculosis in a Low-Prevalence Area
Integrating the Xpert MTB/RIF Assay into a Diagnostic Workflow for Rapid Detection of Mycobacterium tuberculosis in a Low-Prevalence Area
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DOI：
10.1128/jcm.00151-13
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发表时间：
2013-07-01
影响因子：
9.4
通讯作者：
Bloemberg, Guido V.
中科院分区：
文献类型：
--
作者：
Deggim, Vanessa;Somoskovi, Akos;Bloemberg, Guido V.
Xpert MTB/RIF检测试剂盒是一种快速、全自动实时PCR检测试剂盒。在2年期间评价了Xpert MTB/RIF assay作为紧急临床标本初步筛选检测的性能。结果表明，用Xpert MTB/RIF检测试剂盒取代涂片显微镜检查有助于实验室处理，并提高了结核分枝杆菌检测的灵敏度和特异性。
The Xpert MTB/RIF assay is a rapid and fully automated real-time PCR assay. The performance of the Xpert MTB/RIF assay as a primary screening test for urgent clinical specimens was evaluated during a 2-year period. The results showed that replacing smear microscopy with the Xpert MTB/RIF assay facilitates laboratory handling and improves the sensitivity and specificity of Mycobacterium tuberculosis detection.