Understanding location- and feature-based processing along the human intraparietal sulcus
Understanding location- and feature-based processing along the human intraparietal sulcus
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DOI：
10.1152/jn.00404.2016
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发表时间：
2016-09-01
影响因子：
2.5
通讯作者：
Xu, Yaoda
中科院分区：
文献类型：
--
作者：
Bettencourt, Katherine C.;Xu, Yaoda
基于不同的认知任务和映射方法，人类顶内沟（IPS）被细分为多种不同的组织模式。整个IPS的地形组织区域的存在表明在这个大脑区域中有很强的基于位置的处理。然而，视觉短期记忆（VSTM）研究已经表明，虽然下IPS区域（下IPS）中的区域参与基于位置的对象个性化和选择，但是上级IPS（上级IPS）中的区域主要编码和存储对象特征信息。在这里，我们确定了这两个VSTM IPS区域相对于个人参与者的地形IPS区域和不同的IPS区域在基于位置和特征的处理中的作用的本地化。解剖学上，下IPS显示与局部IPS区域重叠85.2%，在V3 A和V3 B中观察到最大重叠，上级IPS显示总体重叠73.6%，在IPS 0 -2中观察到最大重叠。在功能上，IPS区域之间似乎存在部分重叠，涉及基于位置和基于特征的处理，更多的下部和内侧区域显示出更强的基于位置的处理，更多的上级和外侧区域显示出更强的基于特征的处理。总之，这些结果表明，理解IPS在视觉认知中的多重性质可能不会减少到检查不同IPS地形区域的功能，而是只能通过理解不同任务和方法识别的区域如何相互共定位来完成。
Based on different cognitive tasks and mapping methods, the human intraparietal sulcus (IPS) has been subdivided according to multiple different organizational schemes. The presence of topographically organized regions throughout IPS indicates a strong location-based processing in this brain region. However, visual short-term memory (VSTM) studies have shown that while a region in the inferior IPS region (inferior IPS) is involved in object individuation and selection based on location, a region in the superior IPS (superior IPS) primarily encodes and stores object featural information. Here, we determined the localization of these two VSTM IPS regions with respect to the topographic IPS regions in individual participants and the role of different IPS regions in location-and feature-based processing. Anatomically, inferior IPS showed an 85.2% overlap with topographic IPS regions, with the greatest overlap seen in V3A and V3B, and superior IPS showed a 73.6% overall overlap, with the greatest overlap seen in IPS0-2. Functionally, there appeared to be a partial overlap between IPS regions involved in location-and feature-based processing, with more inferior and medial regions showing a stronger location-based processing and more superior and lateral regions showing a stronger feature-based processing. Together, these results suggest that understanding the multiplex nature of IPS in visual cognition may not be reduced to examining the functions of the different IPS topographic regions, but rather, it can only be accomplished by understanding how regions identified by different tasks and methods may colocalize with each other.