Measurement of the Clausius-Mossotti factor of generalized dielectrophoresis

Measurement of the Clausius-Mossotti factor of generalized dielectrophoresis
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DOI:
10.1063/1.4866344
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发表时间:
2014-02-24
影响因子:
4
通讯作者:
Yang, P. C.
Yang, P. C.
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
Lo, Y. J.;Lin, Y. Y.;Yang, P. C.

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广义介电泳的力和扭矩,包括传统介电泳、电旋转和行波介电泳,取决于克劳修斯-莫索蒂因子K-r和K-i的实部和虚部,这对于生物细胞来说是未知的,但在文献中很少测量。提出并验证了测量球形颗粒 K-r 和 K-i 的方法,该方法分别基于设计微通道内部近似径向电场和行波电场中的力平衡。该方法通过测量三种人类癌细胞的 K-r 和 K-i 光谱得到证明,这也为细胞操作和表征提供了定量结果。 (C) 2014 AIP 出版有限责任公司。
The force and torque of generalized dielectrophoresis, including conventional dielectrophoresis, electrorotation, and travelling wave dielectrophoresis, depend on the real and imaginary parts of the Clausius-Mossotti factor, K-r and K-i, which are unknown for biological cells, yet seldom measured in the literature. Methods are proposed and validated for measuring K-r and K-i of spherical particles, based on the force balances in an approximate radial and a travelling wave electric field, respectively, inside designed micro channels. The methods were demonstrated by measuring K-r and K-i spectra of three human cancer cells, which also provide quantitative results for cell manipulation and characterization. (C) 2014 AIP Publishing LLC.