Radioligand Therapy in Prostate Cancer Using PSMA Ligands

Radioligand Therapy in Prostate Cancer Using PSMA Ligands
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使用 PSMA 配体治疗前列腺癌的放射配体

DOI:
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发表时间:
2020
期刊:
影响因子:
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通讯作者:
K. Rahbar
K. Rahbar
中科院分区:
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文献类型:
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作者:
R. Seifert;K. Rahbar

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转移性去势抵抗性前列腺癌 (mCRPC) 患者的治疗选择有限。遵循治疗诊断策略,通过诊断和治疗放射性同位素靶向前列腺特异性膜抗原 (PSMA) 是 mCRPC 管理中不断发展的领域。与治疗性放射性同位素结合的 PSMA 配体的初步结果显示出良好的功效和适度的副作用。在本章中,我们介绍了 PSMA 靶向治疗方案的历史概述和当前的临床程序指南。
Patients with metastatic castration-resistant prostate cancer (mCRPC) have limited therapeutic options. Following a theranostics strategy, targeting the prostate-specific membrane antigen (PSMA) by diagnostic and therapeutic radioisotopes is an evolving field in the management of mCRPC. Initial results of PSMA ligands that are conjugated with therapeutic radioisotopes show good efficacy and modest side effects. In this chapter, we present a historical outline and current clinical procedure guidelines for PSMA-targeted therapy regimes.
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发表时间: 2008-03-01
影响因子: 45.3
作者:
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