Aryl Radical Addition to Curvatures of Carbon Nanohorns for Single-Molecule-Level Molecular Imaging
Aryl Radical Addition to Curvatures of Carbon Nanohorns for Single-Molecule-Level Molecular Imaging
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DOI：
10.1246/bcsj.20200232
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发表时间：
2020-12-01
影响因子：
4
通讯作者：
Nakamura, Eiichi
中科院分区：
文献类型：
--
作者：
Kamei, Ko;Shimizu, Toshiki;Nakamura, Eiichi
用原子分辨电子显微镜实时成像单个分子和分子组件的动力学是一种新兴的实验方法，它可以获得关于分子运动和反应的单分子水平的信息。该方法的中心思想是用化学鱼钩捕捉溶液中的单分子和分子组装，并将它们带入电子显微镜的纳米级视野。在此，我们报道了在碳纳米角上安装芳香族基团，方法是将原位生成的芳基自由基选择性地添加到石墨表面正负曲率的应变区。我们可以引入包括取代碳基和杂环在内的各种芳香族部分，它们可以通过酰胺键的形成和van der Waals相互作用从溶液中捕获分子。
Real-time imaging of the dynamics of single molecules and molecular assemblies with atomic-resolution electron microscopy is an emerging experimental methodology to obtain single-molecule-level information on molecular motions and reactions. The central idea of the methodology is to capture single molecules and molecular assemblies in solution with a chemical fishhook and bring them into the nm-scale view field of the electron microscope. We report herein the installation of aromatic groups on carbon nanohorns by the addition of in situ-generated aryl radicals from arylamines selectively to strained areas of positive and negative curvature on the graphitic surface. We can introduce a variety of aromatic moieties including substituted carbo- and heteroaromatics, which can capture molecules from their solution through amide bond formation and van der Waals interaction.