Effects of the COVID-19 Epidemic on Hospital Admissions for Non-Communicable Diseases in a Large Italian University-Hospital: A Descriptive Case-Series Study.
Effects of the COVID-19 Epidemic on Hospital Admissions for Non-Communicable Diseases in a Large Italian University-Hospital: A Descriptive Case-Series Study.
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DOI：
10.3390/jcm10040880
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发表时间：
2021-02-21
影响因子：
3.9
通讯作者：
Sverzellati N
中科院分区：
文献类型：
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作者：
Caminiti C;Maglietta G;Meschi T;Ticinesi A;Silva M;Sverzellati N
背景资料：COVID-19疫情的应对措施可能对其他医疗状况的管理产生负面影响，这一点越来越令人担忧。研究方法：一项回顾性描述性病例系列研究在受疫情严重打击的意大利北方一所大型大学医院进行。结果：2020年2月23日至5月14日期间，4160名（52%）COVID-19患者和3778名（48%）非COVID-19患者住院。COVID-19入院人数在3月下半月达到峰值，这一时期的特点是死亡率极高（27. 4%）。2020年的入院人数与2019年相似，但COVID-19患者逐渐占据了所有可用床位。对比2020年的COVID-19与非COVID-19入院人数，发现所有年龄层及性别均存在显著差异。具体而言，COVID-19患者年龄较大，主要为男性，并表现出更多的合并症。总体而言，2020年的非传染性疾病（NCD）入院人数比2019年下降了约三分之一。观察到急性心肌梗死（-78，-33.9%），脑血管疾病（-235，-41.5%）和癌症（-368，-31.9%）的统计学显著下降。虽然前两种疾病在COVID-19患者和非COVID-19患者之间的分布似乎相等，但慢性NCD在前者中的发生率在统计学上显著更高，但癌症除外，后者在COVID-19患者中的发生率较低。结论：预防对其他疾病患者的附带损害应成为流行病应对计划的一个组成部分。需要前瞻性队列研究来了解长期影响。
Background: Concern is growing about the negative consequences that response measures to the COVID-19 epidemic may have on the management of other medical conditions. Methods: A retrospective descriptive case-series study conducted at a large University-hospital in northern Italy, an area severely hit by the epidemic. Results: Between 23 February and 14 May 2020, 4160 (52%) COVID-19 and 3778 (48%) non-COVID-19 patients were hospitalized. COVID-19 admissions peaked in the second half of March, a period characterized by an extremely high mortality rate (27.4%). The number of admissions in 2020 was similar to 2019, but COVID-19 patients gradually occupied all available beds. Comparison between COVID-19 and non-COVID-19 admissions in 2020 revealed significant differences concerning all age classes and gender. Specifically, COVID-19 patients were older, predominantly male, and exhibited more comorbidities. Overall, admissions for non-communicable diseases (NCDs) in 2020 vs. 2019 dropped by approximately one third. Statistically significant reductions were observed for acute myocardial infarction (−78, −33.9%), cerebrovascular disease (−235, −41.5%), and cancer (−368, −31.9%). While the first two appeared equally distributed between COVID-19 and non-COVID-19 patients, chronic NCDs were statistically significantly more frequent in the former, except cancer, which was less frequent in COVID-19 patients. Conclusions: Prevention of collateral damage to patients with other diseases should be an integral part of epidemic response plans. Prospective cohort studies are needed to understand the long-term impact.
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影响因子：
5.7
作者：
Mégarbane B;Bourasset F;Scherrmann JM
通讯作者：
Scherrmann JM
影响因子：
39.3
作者：
De Rosa, Salvatore;Spaccarotella, Carmen;Indolfi, Ciro
通讯作者：
Indolfi, Ciro
影响因子：
3.3
作者：
Brandes, Alba A.;Ardizzoni, Andrea;Pinto, Carmine
通讯作者：
Pinto, Carmine
影响因子：
5.8
作者：
Al-Shamsi, Humaid O.;Alhazzani, Waleed;Xie, Conghua
通讯作者：
Xie, Conghua
DOI：
10.1377/hlthaff.2020.00980
发表时间：
2020-11
期刊：
Health affairs (Project Hope)
影响因子：
--
作者：
Birkmeyer JD;Barnato A;Birkmeyer N;Bessler R;Skinner J
通讯作者：
Skinner J