Role of antiretroviral treatment in prolonging QTc interval in HIV-positive patients

Role of antiretroviral treatment in prolonging QTc interval in HIV-positive patients
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DOI:
10.1016/j.jinf.2006.11.001
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发表时间:
2007-06-01
影响因子:
28.2
通讯作者:
Petrosillo, Nicola
Petrosillo, Nicola
中科院分区:
医学1区
文献类型:
--
作者:
Chinello, Pierangelo;Lisena, Francesco P.;Petrosillo, Nicola

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目的:我们的研究的目的是评估QTc间期延长的患病率在一组HIV感染individuals.Methods:所有650例HIV感染者随访在我们的门诊进行心电图记录,并评估相关的危险因素。采用巢式病例对照研究方法,以QTc > 0.44s的HIV感染者64例为病例组,256例性别、年龄、QTc间期匹配的HIV阳性者为对照组(1:4)
Objectives: The aims of our study were to assess the prevalence of QTc prolongation in a group of HIV-infected individuals and to evaluate the associated risk factors.Methods: All the 650 HIV-infected patients followed up at our outpatient clinic underwent ECG recording. A "nested" case-control study was performed using as cases 64 HIV-infected patients with QTc >0.44 s and as controls (1:4) 256 HIV-positive subjects matched by gender and age with QTc interval