Comparison of sensitization and prevalence of Japanese cedar pollen and mite-induced perennial allergic rhinitis between 2006 and 2016 in hospital workers in Japan
Comparison of sensitization and prevalence of Japanese cedar pollen and mite-induced perennial allergic rhinitis between 2006 and 2016 in hospital workers in Japan
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DOI：
10.1016/j.alit.2020.07.004
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发表时间：
2021-01-01
影响因子：
6.8
通讯作者：
Fujieda, Shigeharu
中科院分区：
文献类型：
--
作者：
Sakashita, Masafumi;Tsutsumiuchi, Toshiki;Fujieda, Shigeharu
背景：过敏性鼻炎（AR）的患病率在全球范围内不断增加，主要是由于抗原暴露的增加。我们在2006年对福井大学医院及其附属医院的工作人员进行了流行病学研究。有1540名年龄≥ 20岁的参与者，日本雪松（JC）花粉症和螨引起的常年性变应性鼻炎（PAR）的发生率分别为36.8%和15.8%。2016年，我们进行了第二次调查。方法：根据问卷调查和抗原特异性免疫球蛋白E（IgE）水平的数据，分析JC花粉和螨致敏率以及JC花粉症和螨诱导PAR的患病率。JC花粉总致敏率为57.8%（851/1472），JC花粉症总患病率为40.8%（601/ 1472）。总致敏率为41.4%（610/1472），总PAR患病率为18.8%（276/1472）。JC花粉症和螨引起的PAR的总患病率在十年内显著增加。在参与2006年和2016年横断面研究的334人中，13%的JC花粉症和36%的螨诱导的PAR缓解。然而，由于新发病例的数量较高，缓解病例的数量，在患病率略有增加，观察到超过十年。结论：JC花粉症和螨引起的PAR的患病率继续呈上升趋势，伴随着抗原暴露的增加。JC花粉症的缓解率特别低。日本过敏学会版权所有（C）2020。制作和主办：Elsevier B. V.
Background: The prevalence of allergic rhinitis (AR) is increasing worldwide, mainly due to an increase in antigen exposure. We conducted an epidemiological study involving the staff of the University of Fukui Hospital and its associated hospital in 2006. There were 1540 participants aged >= 20 years, and the rates of Japanese cedar (JC) pollinosis and mite-induced perennial allergic rhinitis (PAR) were 36.8% and 15.8%, respectively. In 2016, we conducted a second survey.Methods: The rate of sensitization to JC pollen and mites and the prevalence of JC pollinosis and miteinduced PAR were analyzed based on data from questionnaires and antigen-specific immunoglobulin E (IgE) levels.Results: In the present study, we analyzed data of 1472 participants aged between 20 and 59 years. Total sensitization to JC pollen and total prevalence of JC pollinosis were 57.8% (851/1472) and 40.8% (601/ 1472), respectively. Total sensitization to mites and total prevalence of mite-induced PAR were 41.4% (610/1472) and 18.8% (276/1472), respectively. Total prevalence of JC pollinosis and mite-induced PAR increased significantly over a decade. Among the 334 people who participated in the 2006 and 2016 cross-sectional studies, 13% of JC pollinosis and 36% of mite-induced PAR experienced remission. However, since the number of new onset cases was higher that the number of remission cases, a slight increase in prevalence was observed over a decade.Conclusions: The prevalence of JC pollinosis and mite-induced PAR continues to show increasing trends, accompanied by an increase in antigen exposure. The remission rate of JC pollinosis was particularly low. Copyright (C) 2020, Japanese Society of Allergology. Production and hosting by Elsevier B.V.